Studying of multidrug resistance proteins, NIHI, Dept. of Cell Metabolism, 1994-;
Since 1994 October I have been working in the laboratory of Prof. Balázs Sarkadi at the NIHI, taking part in our complex study on the human multidrug resistance proteins. My research focuses on the membrane topology and transport properties of the human multidrug resistance associated protein (MRP1); creating a mathematical model for kinetic characterisation of P-glycoprotein function; developing a double labeling method to simultaneous measurement of quantity and function of multidrug resistance proteins by a single cell digital imaging system; supporting the clinical diagnosis of multidrug resistance;